Heparin given in clinical doses causes a transient increase in lipoprotein lipase release into the circulation. This may initially result in increased plasma lipolysis, followed by a transient decrease in triglyceride clearance.
Soya bean oil has a natural content of vitamin K1. The content is however so low in SMOFlipid 20% that it is not expected to significantly influence the coagulation process in patients treated with coumarin derivatives.